Endocrine Abstracts

Background: Only 10 cases of Grave’s disease coexistencing with a TSH-secreting pituitary adenoma (TSHoma) have been reported to date. We present a patient with a TSHoma identified based on the biochemical pattern developing while on treatment with anti-thyroid medications initiated after establishing the diagnosis Grave’s disease.Case report: A 44-year-old Caucasian lady presented with unintentional weight loss. Physical examination revealed d...

Introduction: Amyloid goiter (AG) may be associated with either primary amyloidosis (deposit of amyloid protein AL) or secondary amyloidosis (deposit of amyloid protein AL) in chronic inflammatory diseases including tuberculosis, cystic fibrosis, ulcerative colitis, ankylosing spondylitis and familial Mediterranean fever. To our knowledge, this is the first case of AG concomitant with PTC in a patient with HIV infection.Case presentation: 67-year-old mal...

Objective: Diabetic mastopathy (DMP) is an uncommon fibrous disease of the breast, most commonly found in premenopausal women with type 1 diabetes exposed to long-standing insulin therapy. Often mimicking breast cancer clinically and on imaging, this condition poses a diagnostic challenge requiring pathological confirmation.Case presentation: A 68-year-old woman with type 1 DM and a family history of breast cancer in paternal aunt had an abnormal screeni...

Introduction: Sarcoidosis is a multisystem noncaseating granulomatous disease with prevalence of 40/100 000. One percent of patients with sarcoidosis have isolated neurosarcoidosis, few cases involve the hypothalamus/pituitary (65 reported cases from 2002 to 2014). We present a case of hypothalamic-pituitary sarcoidosis with hypothermia (one case reported between 2002 and 2014), leptomeningitis, diabetes insipidus and pan-hypopituitarism.Case report: Fam...

Introduction: Calcium metabolism during pregnancy changes significantly but ionized calcium level remains normal. During pregnancy, there is two-fold increase in intestinal calcium absorption mediated by increase in 1,25-dihydroxyvitamin D. Hypercalcemia in pregnancy is uncommon and most reported cases are primary hyperparathyroidism.Case report: A 18-year-old 10 weeks’ pregnant African American female presented to hospital with epigastric pain, nau...